The Clinical Investigation Center (CIC) has a pivotal role within the DRZ, namely to longitudinally determine primary mental outcome measures, i.e., to assess and quantify resilience and is therefore the central organizational and recruitment backbone for human studies at the DRZ. This will be accomplished through the Gutenberg Brain Study (GBS) [bitte Verlinkung innerhalb der Webseite hier einfügen] and its affiliated studies. The CIC will recruit and characterize all individuals who subsequently enter projects being pursued by the DRZ. Working in close collaboration with the NIC [bitte Verlinkung innerhalb der Webseite hier einfügen], as exemplified by the Mainz Resilience Project (MARP) [bitte Verlinkung innerhalb der Webseite hier einfügen], it aims to identify key neural mechanisms that predict resilient outcomes and to probe the causal effect of these mechanisms on resilience via dedicated training interventions. Since resilience factors against everyday stressors have not systematically been defined, the CIC will initiate a register-based longitudinal study which is rooted in the GBS. A third function of the CIC within the DRZ is to carry out intervention studies, including psychological training programs, pharmacological trials or neurotechnical intervention (e.g., neurofeedback, transcranial stimulation). Thus, the CIC will act as the central executive platform of the DRZ, facilitating the translation of research outcomes from various research areas to human studies. The CIC will conduct these longitudinal studies using cutting-edge ecological momentary assessment and intervention (EMA/EMI) technology.
Further information about projects and staff of the CIC can be found here.
Dr. Oliver Tüscher
Department of Psychiatry and Psychotherapy
University Medical Center of the Johannes Gutenberg University
Untere Zahlbacher Str. 8